The REPS1 Antibody (PACO22542) is a key tool for researchers studying the REPS1 protein, an essential component involved in intracellular trafficking pathways. This polyclonal antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it a reliable choice for Western blot applications. By targeting the REPS1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it invaluable for studies in molecular biology and cellular transport mechanisms.REPS1 is known for its role in regulating the transport of cargo vesicles within cells, and its dysfunction has been linked to various diseases, including neurodegenerative disorders and metabolic syndromes.
By investigating the functions of REPS1, researchers can gain insights into the mechanisms underlying these conditions and develop potential therapeutic interventions targeting this protein. The REPS1 Antibody is a valuable tool for unraveling the complexities of intracellular trafficking and advancing our understanding of disease pathology.
Antibody Name:
REPS1 Antibody (PACO22542)
Antibody SKU:
PACO22542
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from C-terminal of human REPS1.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from rat heart cells, using REPS1 antibody.
Background:
May coordinate the cellular actions of activated EGF receptors and Ral-GTPases By similarity.
Synonyms:
RALBP1; RALBP1 associated Eps domain containing 1; RalBP1-associated Eps domain-containing protein 1; RalBP1-interacting protein 1; REPS1
UniProt Protein Function:
May coordinate the cellular actions of activated EGF receptors and Ral-GTPases.
UniProt Protein Details:
NCBI Summary:
This gene encodes a signaling adaptor protein with two EH domains that interacts with proteins that participate in signaling, endocytosis and cytoskeletal changes. The encoded protein has been found in association with intersectin 1 and Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1 when intersectin 1 was isolated from clathrin-coated pits. The encoded protein has also been shown to interact with amphiphysin, a cytoplasmic protein at the surface of synaptic vesicles. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]
