The RIC8A Antibody (CAB10393) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits strong reactivity with human samples and is specifically validated for use in Western blotting applications.Synembryn-A, a member of the synuclein family, is known for its role in regulating synaptic transmission and vesicle trafficking in neurons. Its function in these processes implicates it in neurological diseases such as Parkinson's and Alzheimer's. By targeting Synembryn-A with this antibody, researchers can investigate its expression levels and localization in different cell types, aiding in the understanding of its involvement in neurodegenerative disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
RIC8A Antibody
SKU:
CAB10393
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
RIC8, RIC8A
Positive Sample:
Raji, HeLa, HepG2, 293T, DU145, Mouse brain, Rat brain
Cellular Localization:
Cell Membrane, Cytoplasm.
Calculated MW:
60kDa
Observed MW:
60kDa
Predicted to enable G-protein alpha-subunit binding activity; GTPase activator activity; and guanyl-nucleotide exchange factor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within several processes, including basement membrane organization; gastrulation; and visual learning. Predicted to be located in membrane. Predicted to be active in cytoplasm and plasma membrane.
Purification Method
Affinity purification
Gene ID
60626
RRID
AB_2757941
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using RIC8A Rabbit pAb (CAB10393) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 20s.
