The RIMKLA Polyclonal Antibody (PACO22579) is a valuable tool for research involving RIMKLA, a key protein involved in mitochondrial function and cellular metabolism. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the RIMKLA protein, researchers can selectively detect and analyze its expression in a variety of cell types, making it an essential reagent for studies in mitochondrial biology and metabolic disease research.RIMKLA, also known as mitochondrial lysine tRNA ligase, is essential for protein synthesis within mitochondria and is involved in maintaining cellular energy production.
Dysregulation of RIMKLA has been implicated in various metabolic disorders, making it an attractive target for research into conditions such as diabetes, obesity, and mitochondrial dysfunction. Understanding the role of RIMKLA in these pathways is crucial for developing targeted therapies aimed at improving mitochondrial function and metabolic health.
Antibody Name:
RIMKLA Antibody (PACO22579)
Antibody SKU:
PACO22579
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from internal of human RIMKA.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from Jurkat cells, HuvEc cells and COS cells, using RIMKA antibody.
Background:
Catalyzes the synthesis of N-acetyl-L-aspartyl-L-glutamate (NAAG) and N-acetyl-L-aspartyl-L-glutamyl-L-glutamate.
Synonyms:
ribosomal protein S6 modification-like A; RIMKA;
UniProt Protein Function:
Catalyzes the synthesis of N-acetyl-L-aspartyl-L-glutamate (NAAG) and N-acetyl-L-aspartyl-L-glutamyl-L-glutamate.
ribosomal modification protein rimK like family member A
NCBI Official Symbol:
RIMKLAÂ Â
NCBI Official Synonym Symbols:
NAAGS; FAM80A; NAAGS-IIÂ Â
NCBI Protein Information:
N-acetylaspartylglutamate synthase A
UniProt Protein Name:
N-acetylaspartylglutamate synthase A
UniProt Synonym Protein Names:
N-acetylaspartylglutamylglutamate synthase A (EC:6.3.2.42By similarityManual assertion inferred from sequence similarity toiUniProtKB:Q6PFX8Â (RIMKA_MOUSE)); Ribosomal protein S6 modification-like protein A
