Description
RPS11 Antibody (PACO29188)
The RPS11 Antibody (PAC029188) is a high-quality polyclonal antibody designed for research involving RPS11, a ribosomal protein essential for protein synthesis. This antibody, raised in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to the RPS11 protein, enabling accurate detection and analysis in various cell types.RPS11, a component of the 40S small ribosomal subunit, plays a crucial role in the translation process by aiding in the assembly of the ribosome and promoting protein synthesis. Dysregulation of RPS11 has been implicated in various diseases, including cancer and genetic disorders, making it a promising target for research in these areas.
Understanding the function of RPS11 is essential for unraveling its role in disease pathogenesis and identifying potential therapeutic interventions.Overall, the RPS11 Antibody (PAC029188) is a valuable tool for researchers conducting studies in molecular biology, cancer biology, and genetic disorders. Its high specificity and sensitivity make it ideal for investigating the role of RPS11 in various cellular processes and disease mechanisms.
| Antibody Name: | RPS11 Antibody (PACO29188) |
| Antibody SKU: | PACO29188 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human 40S ribosomal protein S11 protein (2-158AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: 40S ribosomal protein S11 antibody at 2µg/ml + 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 18 kDa Observed band size: 18 kDa . |
 | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO29188 at dilution of 1:100. |
| Synonyms: | 40S ribosomal protein S11 (Small ribosomal subunit protein uS17), RPS11 |
| UniProt Protein Function: | RPS11: a member of the S17P family of ribosomal proteins that is a component of the 40S subunit. This gene is co-transcribed with the small nucleolar RNA gene U35B, which is located in the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Jul 2012]Protein type: Ribosomal; RNA-binding; TranslationChromosomal Location of Human Ortholog: 19q13.3Cellular Component: cytoplasm; cytosol; focal adhesion; membrane; nucleolus; nucleoplasmMolecular Function: protein binding; structural constituent of ribosomeBiological Process: mRNA catabolic process, nonsense-mediated decay; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; translation; translational initiation; viral transcription |
| UniProt Protein Details: | |
| NCBI Summary: | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the S17P family of ribosomal proteins that is a component of the 40S subunit. This gene is co-transcribed with the small nucleolar RNA gene U35B, which is located in the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Jul 2012] |
| UniProt Code: | P62280 |
| NCBI GenInfo Identifier: | 50403609 |
| NCBI Gene ID: | 6205 |
| NCBI Accession: | P62280.3 |
| UniProt Secondary Accession: | P62280,P04643, Q498Y6, Q6IRY0, B2R4F5 |
| UniProt Related Accession: | P62280 |
| Molecular Weight: | 18,431 Da |
| NCBI Full Name: | 40S ribosomal protein S11 |
| NCBI Synonym Full Names: | ribosomal protein S11 |
| NCBI Official Symbol: | RPS11Â Â |
| NCBI Official Synonym Symbols: | S11Â Â |
| NCBI Protein Information: | 40S ribosomal protein S11 |
| UniProt Protein Name: | 40S ribosomal protein S11 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Ribosomal protein |
| UniProt Gene Name: | RPS11Â Â |
| UniProt Entry Name: | RS11_HUMAN |
| Antibodies |
| RPS11 Antibody (PACO04965) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
