The RPS11 Polyclonal Antibody (PAC022091) is a valuable tool for research involving RPS11, a ribosomal protein essential for protein synthesis. This antibody, generated in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By targeting the RPS11 protein, this antibody facilitates detection and analysis in various cell types, making it an ideal choice for studies in molecular biology and ribosome function.
RPS11, a component of the 40S ribosomal subunit, plays a crucial role in coordinating the translation of messenger RNA into proteins. Its function in protein synthesis makes it a key target for research into mechanisms of gene expression and regulation. By studying RPS11, researchers can gain insights into fundamental cellular processes and potential therapeutic targets in diseases involving dysregulation of protein synthesis.
Antibody Name:
RPS11 Antibody (PACO22091)
Antibody SKU:
PACO22091
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from internal of human RPS11.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HeLa cells and Jurkat cells, using RPS11 antibody.
Background:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the S17P family of ribosomal proteins that is a component of the 40S subunit. This gene is co-transcribed with the small nucleolar RNA gene U35B, which is located in the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome.
Synonyms:
40S ribosomal protein S11; ribosomal protein S11; RS11;
UniProt Protein Function:
RPS11: a member of the S17P family of ribosomal proteins that is a component of the 40S subunit. This gene is co-transcribed with the small nucleolar RNA gene U35B, which is located in the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Jul 2012]Protein type: Ribosomal; RNA-binding; TranslationChromosomal Location of Human Ortholog: 19q13.3Cellular Component: cytoplasm; cytosol; focal adhesion; membrane; nucleolus; nucleoplasmMolecular Function: protein binding; structural constituent of ribosomeBiological Process: mRNA catabolic process, nonsense-mediated decay; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; translation; translational initiation; viral transcription
UniProt Protein Details:
NCBI Summary:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the S17P family of ribosomal proteins that is a component of the 40S subunit. This gene is co-transcribed with the small nucleolar RNA gene U35B, which is located in the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Jul 2012]
