The RPS6KA3 Polyclonal Antibody (CAB5436) is a powerful tool for researchers studying RPS6KA3, a serine/threonine protein kinase involved in cell growth and proliferation. This antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By targeting the RPS6KA3 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in the fields of cell biology, oncology, and molecular biology.
RPS6KA3, also known as ribosomal protein S6 kinase A3, plays a crucial role in cellular signaling pathways that regulate gene expression, protein synthesis, and cell cycle progression. Dysregulation of RPS6KA3 has been implicated in various diseases, including cancer, cardiovascular disorders, and neurological conditions. By understanding the function and regulation of RPS6KA3, researchers can gain valuable insights into disease mechanisms and potentially identify new therapeutic targets for intervention.
Product Name:
RPS6KA3 Rabbit Polyclonal Antibody
SKU:
CAB5436
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 68-327 of human RPS6KA3 (NP_004577.1).
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS).
Purification Method:
Affinity purification
Gene ID:
6197
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse lung, using RPS6KA3 Rabbit pAb (CAB5436) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
