The NOGO Receptor 1 (RTN4R) Monoclonal Antibody (CAB3952) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, shows high specificity and sensitivity in detecting the Nogo receptor in various cell types. Validated for use in Western blot applications, it allows for accurate and reliable analysis of the Nogo receptor protein.The Nogo receptor plays a crucial role in inhibiting neural regeneration and plasticity, making it a key target for research in the fields of neuroscience and neurology. By understanding the function and regulation of the Nogo receptor, researchers may uncover new insights into neurological disorders such as multiple sclerosis, spinal cord injuries, and neurodegenerative diseases.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
NOGO Receptor 1 (RTN4R) Monoclonal Antibody
SKU:
CAB3952
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Clone Number:
ARC0872
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
NGR, NOGOR, NOGO Receptor 1 (RTN4R)
Positive Sample:
A549, U-87MG, Mouse brain
Cellular Localization:
Cell Membrane, Gpi-Anchor, Lipid-Anchor.
Calculated MW:
51kDa
Observed MW:
70kDa
This gene encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.
Purification Method
Affinity purification
Gene ID
65078
RRID
AB_2863162
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using NOGO Receptor 1 (RTN4R) Rabbit mAb (CAB3952) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3min.
