The S100A7/Psoriasin Polyclonal Antibody (CAB22026) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is specifically reactive with human samples and is validated for use in Western blot applications. By binding to the S100A7 protein, this antibody allows for accurate detection and analysis in various cell types, making it an ideal tool for researchers in the fields of dermatology, oncology, and inflammation.S100A7, a member of the S100 family of calcium-binding proteins, is known for its involvement in inflammatory skin disorders such as psoriasis. It has also been implicated in promoting tumorigenesis and tumor progression in various cancers.
This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
S100A7/Psoriasin Polyclonal Antibody
SKU:
CAB22026
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.
Purification Method
Affinity purification
Gene ID
6278
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from SK-BR-3 cells, using S100A7/Psoriasin Rabbit pAb (CAB22026) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Immunohistochemistry analysis of paraffin-embedded Human cervix cancer using S100A7/Psoriasin Rabbit pAb (CAB22026) at dilution of 1:200 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
