The S100PBP Polyclonal Antibody (PACO17041) is a key tool for researchers studying S100PBP, a protein involved in various cellular processes. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blotting applications. By binding to the S100PBP protein, researchers can easily detect and analyze its expression in different cell types, making it a versatile tool for studies in cell biology and cancer research.S100PBP, also known as S100P-binding protein, is a critical player in cellular signaling pathways and is implicated in cancer progression and metastasis.
Its role in regulating cell behavior and survival makes it an attractive target for investigations into cancer biology and potential therapeutic interventions. Understanding the functions of S100PBP will provide valuable insights into its contributions to disease development and progression, ultimately guiding the development of targeted therapies for cancer patients.
Antibody Name:
S100PBP Antibody (PACO17041)
Antibody SKU:
PACO17041
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:1000-1:2000, WB:1:200-1:1000
Species Reactivity:
Human
Immunogen:
Fusion protein of human S100PBP
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal brain tissue, Primary antibody: PACO17041(S100PBP Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute.
Background:
This gene encodes a protein that was originally identified by its interaction with S100 calcium-binding protein P. Expression of this protein has been reported to be associated with pancreatic ductal adenocarcinoma. Alternatively spliced transcript variants have been described.
Synonyms:
S100P binding protein
UniProt Protein Function:
Subunit structure: Interacts with S100P. Ref.5Subcellular location: Nucleus. Note: Colocalizes with S100P in the nucleus. Ref.5Tissue specificity: Expressed in brain, spleen, and lung. Not detected in pancreas or liver. In pancreas, expressed predominantly in islet cells and to a lesser extent in acinar cells, but not expressed in ductal cells. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias. Detected in pancreatic ductal adenocarcinoma cells (at protein level). Not detected in non-neoplastic ductal epithelium (at protein level). Ref.5 Ref.6Sequence caution: The sequence BAB14335.1 differs from that shown. Reason: Erroneous initiation.
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that was originally identified by its interaction with S100 calcium-binding protein P. Expression of this protein has been reported to be associated with pancreatic ductal adenocarcinoma. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]
