The SAMD9 Polyclonal Antibody (PAC020389) is a valuable tool for researchers studying the SAMD9 protein, which plays a key role in cellular function and immune response regulation. This antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By binding to the SAMD9 protein, it allows for accurate detection and analysis in a variety of cell types, making it ideal for investigations in immunology and cancer research.
SAMD9 is a critical player in immune regulation, acting as a modulator of immune responses and inflammation. Research into the function of SAMD9 is essential for understanding its involvement in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By targeting SAMD9, researchers can gain insights into potential therapeutic strategies for manipulating immune responses in these health conditions.
Antibody Name:
SAMD9 Antibody (PACO20389)
Antibody SKU:
PACO20389
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human SAMD9
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20389(SAMD9 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene encodes a sterile α motif domain-containing protein. The encoded protein localizes to the cytoplasm and may play a role in regulating cell proliferation and apoptosis. Mutations in this gene are the cause of normophosphatemic familial tumoral calcinosis. Alternate splicing results in multiple transcript variants that encode the same protein.
Synonyms:
sterile α motif domain containing 9
UniProt Protein Function:
SAMD9: Defects in SAMD9 are the cause of normophosphatemic familial tumoral calcinosis (NFTC). NFTC is an uncommon life-threatening disorder characterized by massive periarticular, and seldom visceral, deposition of calcified tumors.Protein type: Unknown functionChromosomal Location of Human Ortholog: 7q21.2Cellular Component: intracellular membrane-bound organelle; cytoplasmMolecular Function: protein bindingDisease: Tumoral Calcinosis, Normophosphatemic, Familial
UniProt Protein Details:
NCBI Summary:
This gene encodes a sterile alpha motif domain-containing protein. The encoded protein localizes to the cytoplasm and may play a role in regulating cell proliferation and apoptosis. Mutations in this gene are the cause of normophosphatemic familial tumoral calcinosis. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Jul 2010]
