The SAMD9L Monoclonal Antibody (PAC020390) is a valuable tool for researchers studying the SAMD9L protein, which is involved in various cellular processes including immune regulation and antiviral defense. This antibody, produced in a monoclonal format, exhibits high specificity and sensitivity towards human samples and is perfect for use in immunohistochemistry and immunofluorescence assays.SAMD9L, a member of the sterile alpha motif domain containing protein family, plays a crucial role in innate immunity by triggering antiviral responses and modulating immune signaling pathways.
Its function in immune regulation makes it a promising target for investigating viral infections, autoimmune diseases, and inflammatory disorders. By using the SAMD9L Monoclonal Antibody, researchers can gain valuable insights into the role of SAMD9L in immune response modulation and its potential implications in disease pathology.
Antibody Name:
SAMD9L Antibody (PACO20390)
Antibody SKU:
PACO20390
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human SAMD9L
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20390(SAMD9L Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20390(SAMD9L Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
The deduced protein contains an N-terminal SAM domain. Database analysis indicated that SAMD9L can undergo alternative splicing leading to an alternative coding region. PCR analysis detected SAMD9L in all adult and fetal human tissues examined except some tumor tissues. Orthologs of SAMD9L were detected in all mammals examined but not in chicken, frog, or fish species. Widely expressed in adult and fetal tissues. Variable expression in tumors. Down-regulated in breast cancer.
Synonyms:
sterile α motif domain containing 9-like
UniProt Protein Function:
SAMD9L: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 7q21.2