The SARS-CoV-2 Spike RBD (N501Y) Monoclonal Antibody (CAB21254) is a high-quality antibody developed for reliable detection and analysis of target proteins. This monoclonal antibody specifically targets the Spike protein receptor binding domain (RBD) with the N501Y mutation, which has been associated with increased transmissibility.Developed using cutting-edge technology, this antibody is highly specific and sensitive, allowing for accurate detection and analysis of the SARS-CoV-2 Spike protein in various sample types. It is validated for use in a variety of applications, including ELISA, Western blot, and immunofluorescence, making it versatile for researchers in the fields of virology, infectious diseases, and vaccine development.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against SARS-CoV-2 samples.
Product Name:
SARS-CoV-2 Spike RBD (N501Y) Monoclonal Antibody
SKU:
CAB21254
Size:
20μL, 100μL
Reactivity:
SARS-CoV-2
Clone Number:
ARC52673
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ The structural proteins of SARS-CoV-2 include the envelope protein (E), spike or surface glycoprotein (S), membrane protein (M) and the nucleocapsid protein (N). The spike glycoprotein is found on the outside of the virus particle and gives coronavirus viruses their crown-like appearance. This glycoprotein mediates attachment of the virus particle and entry into the host cell. S protein is an important target for vaccine development, antibody therapies and diagnostic antigen-based tests.
Purification Method
Affinity purification
Gene ID
43740568
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of recombinant SARS-CoV-2 Spike RBD (N501Y) Protein(RP01258), using SARS-CoV-2 Spike RBD (N501Y) Rabbit mAb (CAB21254) at 1:10000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 100 ng per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3s.
