The SEPT12 Polyclonal Antibody (CAB15564) is a valuable tool for researchers studying SEPT12, a member of the septin family of GTP-binding proteins involved in cytokinesis and cell cycle control. This antibody, generated in rabbits, is highly specific for SEPT12 in human samples and is validated for use in immunofluorescence and immunohistochemistry applications. By targeting the SEPT12 protein, researchers can visualize and study its role in cellular processes, making it a versatile tool for studies in cell biology and cancer research.
SEPT12 is known to play a significant role in maintaining cell structure and function, particularly in the organization of the cytoskeleton and cell division. Dysregulation of SEPT12 has been linked to abnormal cell proliferation and disease states, making it an important target for research into cancer and developmental disorders. Understanding the functions of SEPT12 can provide insights into cell biology and potential therapeutic strategies for diseases characterized by disrupted cell division and organization.
Product Name:
Septin 12 Rabbit Polyclonal Antibody
SKU:
CAB15564
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 189-358 of human Septin 12 (NP_653206.2).
This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
124404
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Septin 12 Rabbit pAb (CAB15564) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
