The SHROOM1 Polyclonal Antibody (PAC01204) is a valuable tool for researchers studying the SHROOM1 protein, a key regulator of cell morphology and tissue architecture. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting SHROOM1 in various experimental settings. Validated for use in Western blot applications, this antibody enables precise detection and quantification of SHROOM1 levels in cell lysates and tissue samples.SHROOM1 plays a crucial role in cell shape changes and tissue organization during development, making it an important target for research in developmental biology and morphogenesis.
Dysregulation of SHROOM1 has been linked to various diseases, including cancer and neurodevelopmental disorders, highlighting its potential as a therapeutic target. By investigating the function and regulation of SHROOM1, researchers can gain insights into disease mechanisms and potential treatment strategies.
SHROOM1: May be involved in the assembly of microtubule arrays during cell elongation. Belongs to the shroom family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Actin-bindingChromosomal Location of Human Ortholog: 5q31.1Cellular Component: microtubule; myosin II complex; cytoplasmMolecular Function: actin filament bindingBiological Process: actin filament bundle formation; cell morphogenesis
UniProt Protein Details:
NCBI Summary:
SHROOM family members play diverse roles in the development of the nervous system and other tissues (Hagens et al., 2006 [PubMed 16615870]).[supplied by OMIM, Mar 2008]
