The SLC25A40 Polyclonal Antibody (PAC038830) is a vital tool for researchers studying the SLC25A40 protein, a member of the solute carrier family of proteins that play essential roles in transporting molecules across mitochondrial membranes. This antibody, produced in rabbits, exhibits high specificity for human samples and is validated for use in Western blot applications. By targeting the SLC25A40 protein, researchers can detect and analyze its expression in various cell types, making it ideal for investigations in mitochondrial biology and metabolic diseases.SLC25A40 is a mitochondrial carrier protein involved in the transport of molecules such as coenzyme A and acetyl-CoA across the inner mitochondrial membrane.
Dysfunction of SLC25A40 has been linked to metabolic disorders and mitochondrial diseases, highlighting its importance in cellular metabolism. Studying the function of SLC25A40 is crucial for understanding the mechanisms underlying these conditions and developing targeted therapies to restore mitochondrial function.Overall, the SLC25A40 Polyclonal Antibody (PAC038830) is a valuable tool for researchers interested in investigating the role of the SLC25A40 protein in mitochondrial function and metabolic disorders. Its high specificity and reactivity with human samples make it a reliable choice for Western blot experiments, enabling detailed analysis of SLC25A40 expression in different cellular contexts.
Immunofluorescent analysis of 293T cells using PACO38830 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human bladder cancer using PACO38830 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human liver tissue using PACO38830 at dilution of 1:100.
Synonyms:
Solute carrier family 25 member 40 (Mitochondrial carrier family protein), SLC25A40, MCFP
UniProt Protein Function:
SLC25A40: Belongs to the mitochondrial carrier familyProtein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 7q21.12Cellular Component: integral to membrane; mitochondrial inner membraneMolecular Function: structural constituent of ribosomeBiological Process: translation; transmembrane transport
UniProt Protein Details:
NCBI Summary:
SLC25A40 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008]