The SLC4A8 Antibody (CAB14825) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the SLC4A8 protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential component for studies in physiology, cell biology, and disease mechanisms.SLC4A8 plays a crucial role in maintaining cellular pH balance and ion homeostasis, making it a key player in physiological processes such as renal function, acid-base regulation, and neuronal excitability.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
SLC4A8 Antibody
SKU:
CAB14825
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
NBC3, NDCBE, SLC4A8
Positive Sample:
U-87MG, SH-SY5Y, Mouse lung, Rat kidney
Cellular Localization:
Membrane, Multi-Pass Membrane Protein.
Calculated MW:
123kDa
Observed MW:
123kDa
The protein encoded by this gene is a membrane protein that functions to transport sodium and bicarbonate ions across the cell membrane. The encoded protein is important for pH regulation in neurons. The activity of this protein can be inhibited by 4,4'-Di-isothiocyanatostilbene-2,2'-disulfonic acid (DIDS). Several transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
9498
RRID
AB_2761704
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC4A8 Rabbit pAb (CAB14825) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
