The SNAPC5 Polyclonal Antibody (PACO03336) is a valuable tool for researchers studying the SNAPC5 protein, a key component of the snRNA-activating protein complex (SNAPc) involved in transcription initiation. This antibody, produced in rabbits, has been validated for use in Western blot applications and is highly reactive with human samples.SNAPC5 plays a critical role in transcriptional regulation by facilitating the assembly of the SNAPc complex and promoting the transcription of small nuclear RNA genes. Understanding the function and regulation of SNAPC5 is essential for unraveling the complexities of gene expression and transcriptional control.
With its ability to specifically bind to SNAPC5, this antibody enables researchers to detect and analyze the protein in various cell types, providing insights into its role in gene regulation and potential implications in diseases such as cancer and developmental disorders. The SNAPC5 Polyclonal Antibody is a valuable tool for studies in molecular biology, genomics, and transcriptional regulation.
Antibody Name:
SNAPC5 Antibody
Antibody SKU:
PACO03336
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
IHC:1:100-1:300
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the N-terminal region of human SNAPC 19.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
SNAPC5; SNAP19; snRNA-activating protein complex subunit 5; SNAPc subunit 5; Small nuclear RNA-activating complex polypeptide 5; snRNA-activating protein complex 19 kDa subunit; SNAPc 19 kDa subunit
UniProt Protein Function:
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.
UniProt Protein Details:
NCBI Summary:
This gene encodes a subunit of the small nuclear RNA (snRNA)-activating protein complex that plays a role in the transcription of snRNA genes. This complex binds to the promoters of snRNA genes transcribed by either RNA polymerase II or III and recruits other regulatory factors to activate snRNA gene transcription. The encoded protein may play a role in stabilizing this complex. A pseudogene of this gene has been identified on chromosome 6. [provided by RefSeq, Jul 2016]
