The SOS1 Antibody (CAB3272) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is raised in rabbits and has been validated for use in various applications, including Western blot and immunohistochemistry.SOS1 is a guanine nucleotide exchange factor (GEF) that activates Ras, a protein involved in cell proliferation and survival. Dysregulation of the SOS1-Ras pathway has been implicated in numerous diseases, including cancer and developmental disorders. By targeting SOS1 with this specific antibody, researchers can investigate its role in these conditions and potentially identify new therapeutic targets.
This antibody is validated for use in - applications and has demonstrated reactivity against - samples.
Western blot analysis of various lysates using SOS1 Rabbit pAb (CAB3272) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
