The SQS/FDFT1 Monoclonal Antibody (CAB4651) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity towards human samples and is ideal for use in Western blot applications to detect and analyze the SQS/FDFT1 protein in various cell types.SQS/FDFT1, also known as squalene synthase, is a key enzyme in the cholesterol biosynthesis pathway, making it a crucial target for research in lipid metabolism and related diseases such as atherosclerosis and metabolic disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
SQS/FDFT1 Monoclonal Antibody
SKU:
CAB4651
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC1077
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.
Purification Method
Affinity purification
Gene ID
2222
RRID
AB_2863317
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using SQS/FDFT1 Rabbit mAb (CAB4651) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3s.
Western blot analysis of lysates from Mouse kidney, using SQS/FDFT1 Rabbit mAb (CAB4651) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
