The SRP72 Polyclonal Antibody (PAC052182) is a valuable tool for researchers studying the SRP72 protein, which is involved in the process of protein targeting and translocation to the endoplasmic reticulum. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for Western blot applications. By binding specifically to SRP72, this antibody allows for the detection and analysis of the protein in various cell types, making it ideal for investigations in the fields of molecular biology and cell biology.SRP72 is an essential component of the signal recognition particle (SRP) complex, which plays a crucial role in protein synthesis and membrane targeting.
Dysregulation of SRP72 has been linked to various human diseases, including neurological disorders and certain types of cancer. Therefore, studying the function and regulation of SRP72 is important for gaining insights into these pathologies and identifying potential therapeutic targets.Overall, the SRP72 Polyclonal Antibody is a reliable reagent for researchers interested in exploring the role of SRP72 in cellular processes and disease mechanisms. Its high specificity and sensitivity make it an invaluable tool for investigating the functions of SRP72 and its potential implications in health and disease.
Antibody Name:
SRP72 Antibody (PACO52182)
Antibody SKU:
PACO52182
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Saccharomyces cerevisiae
Immunogen:
Recombinant Saccharomyces cerevisiae Signal recognition particle subunit SRP72 protein (1-180AA)
Signal-recognition-particle (SRP) assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum (ER) membrane. SRP is required for the cotranslational protein translocation for ER import and preferentially recognizes strongly hydrophobic signal sequences. It is involved in targeting the nascent chain-ribosome (RNC) complex to the ER and is proposed to participate in the arrest of nascent chain elongation during membrane targeting. SRP72 binds the 7S RNA only in presence of SRP68.
Synonyms:
Signal recognition particle subunit SRP72 (Signal recognition particle 72 kDa protein homolog), SRP72
UniProt Protein Function:
Signal-recognition-particle (SRP) assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum (ER) membrane. SRP is required for the cotranslational protein translocation for ER import and preferentially recognizes strongly hydrophobic signal sequences. It is involved in targeting the nascent chain-ribosome (RNC) complex to the ER and is proposed to participate in the arrest of nascent chain elongation during membrane targeting. SRP72 binds the 7S RNA only in presence of SRP68.
