The SSBP1 Polyclonal Antibody (CAB6987) is specifically designed for research involving SSBP1, a key protein involved in DNA replication and repair processes. This antibody, generated in rabbits, exhibits high reactivity towards human samples and has been validated for use in Western blot applications. By binding to the SSBP1 protein, this antibody enables sensitive detection and analysis in various cell types, making it an essential tool for studies in molecular biology and cancer research.SSBP1, also known as single-stranded DNA-binding protein, plays a crucial role in maintaining genomic integrity by interacting with single-stranded DNA during DNA replication and repair.
Its significance in these processes highlights its potential as a target for understanding diseases related to DNA damage, such as cancer and genetic disorders. Investigating the function of SSBP1 is essential for developing targeted therapies aimed at manipulating DNA repair mechanisms for therapeutic purposes.
Product Name:
SSBP1 Rabbit Polyclonal Antibody
SKU:
CAB6987
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-148 of human SSBP1 (NP_001243442.1).
SSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995 [PubMed 7789991]). It is also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].
Purification Method:
Affinity purification
Gene ID:
6742
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using SSBP1 Rabbit pAb (CAB6987) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
