The SUMO3 Polyclonal Antibody (CAB3099) is a high-quality research tool designed for studying SUMO3, a small ubiquitin-like protein involved in post-translational modification. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. It binds to SUMO3, allowing for the detection and analysis of this protein in a variety of cell types, making it an excellent choice for research in molecular biology and cell signaling.SUMO3 plays a crucial role in regulating protein function and localization, particularly in processes such as protein stability, DNA repair, and transcriptional regulation.
Its involvement in these key cellular pathways makes it a valuable target for research into various diseases, including cancer, neurodegenerative disorders, and viral infections. By being able to study the activity of SUMO3, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention.
Product Name:
SUMO3 Rabbit Polyclonal Antibody
SKU:
CAB3099
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SUMO3 (NP_008867.2).
This gene encodes a member of the small ubiquitin-related modifier (SUMO) family of eukaryotic proteins. The encoded protein is covalently conjugated to other proteins via a post-translation modification known as sumoylation. Sumoylation may play a role in a wide variety of cellular processes, including nuclear transport, DNA replication and repair, mitosis, transcriptional regulation, and signal transduction. Alternatively spliced transcript variants encoding distinct proteins have been described.
Purification Method:
Affinity purification
Gene ID:
6612
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from MCF-7 cells, using SUMO3 Rabbit pAb (CAB3099) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
