Synaptotagmin XI (SYT11) Monoclonal Antibody (CAB23089)
The Synaptotagmin XI (SYT11) Monoclonal Antibody (CAB23089) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated through monoclonal methods, shows high specificity and sensitivity for SYT11 in various experimental settings, including Western blot, immunofluorescence, and immunoprecipitation.SYT11 is a key player in synaptic transmission and has been linked to neurological disorders such as Alzheimer's disease and Parkinson's disease.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
Synaptotagmin XI (SYT11) Monoclonal Antibody
SKU:
CAB23089
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC59135
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:1000 - 1:5000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature.
Purification Method
Affinity purification
Gene ID
23208
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using Synaptotagmin XI (SYT11) Rabbit mAb (CAB23089) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
