The TBPL1 Polyclonal Antibody (CAB7575) is a valuable tool for researchers studying the TBPL1 protein, which plays a key role in gene transcription and regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the TBPL1 protein, this antibody enables researchers to detect and analyze TBPL1 expression in various cell types, making it an ideal choice for studies in molecular biology and gene regulation.
TBPL1, also known as TATA box-binding protein-like protein 1, is a crucial component of the transcription complex that regulates gene expression. Its involvement in gene transcription processes makes it a target of interest in research on various diseases and biological pathways. Understanding the function of TBPL1 can provide valuable insights into the mechanisms underlying gene regulation and may lead to the development of novel therapeutic strategies targeting gene expression pathways.
Product Name:
TBPL1 Rabbit Polyclonal Antibody
SKU:
CAB7575
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-186 of human TBPL1 (NP_004856.1).
This gene encodes a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. This gene plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.
Purification Method:
Affinity purification
Gene ID:
9519
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of 293T cells, using TBPL1 antibody (CAB7575) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
