The TERF2 Antibody (CAB16316) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, has been rigorously validated for use in Western blotting and immunofluorescence applications. By specifically recognizing the TERF2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential asset for studies in telomere biology and aging research.TERF2 is a key player in maintaining telomere stability and regulating telomere length, thus playing a crucial role in cellular senescence and genome integrity.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
TERF2 Antibody
SKU:
CAB16316
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
TRF2, TRBF2, TERF2
Positive Sample:
Jurkat, HeLa, Mouse lung
Cellular Localization:
Chromosome, Nucleus, Telomere.
Calculated MW:
60kDa
Observed MW:
70kDa
This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.
Purification Method
Affinity purification
Gene ID
7014
RRID
AB_2772562
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using TERF2 Rabbit pAb (CAB16316) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
