The TFEB Monoclonal Antibody (CAB21928) is a crucial tool for researchers studying TFEB, a transcription factor involved in cellular regulation, particularly in the process of autophagy. This antibody, produced through monoclonal antibody technology, exhibits high specificity and sensitivity for TFEB in various experimental settings.TFEB is known for its role in lysosomal biogenesis, lipid metabolism, and clearance of protein aggregates, making it a key player in cellular homeostasis and response to stress. Dysregulation of TFEB has been linked to a variety of diseases, including neurodegenerative disorders, metabolic syndromes, and cancer.
By targeting TFEB with this antibody, researchers can accurately detect and monitor TFEB expression levels and localization in different cell types and conditions.By understanding the function and regulation of TFEB, researchers can gain valuable insights into disease mechanisms and potential therapeutic targets. The TFEB Monoclonal Antibody (CAB21928) is a valuable tool for advancing research in the fields of cell biology, neurobiology, and metabolic disorders.
Product Name:
TFEB Monoclonal Antibody
SKU:
CAB21928
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 50-173 of human TFEB (NP_009093.1).
Enables DNA-binding transcription factor activity; enzyme binding activity; and transcription cis-regulatory region binding activity. Involved in several processes, including cellular response to amino acid starvation; lysosome localization; and positive regulation of autophagy. Located in cytosol; lysosomal membrane; and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
7942
Clone Number:
ARC53777
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Raji cells, using TFEB Rabbit mAb (CAB21928) at1:8000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
