The THSD1 Polyclonal Antibody (PAC017240) is a valuable tool for researchers studying THSD1, a protein involved in angiogenesis and vascular development. This antibody, produced in rabbits, has high specificity for human samples and is validated for Western blot applications. By binding to the THSD1 protein, this antibody enables researchers to detect and analyze THSD1 expression in a variety of cell types, making it ideal for studies in vascular biology and cancer research.THSD1, also known as Thrombospondin type-1 domain-containing protein 1, plays a crucial role in regulating blood vessel formation and maintenance.
Dysregulation of THSD1 has been implicated in various diseases, including cancer and cardiovascular disorders. By studying the function of THSD1, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets.Overall, the THSD1 Polyclonal Antibody is a valuable tool for researchers looking to advance our understanding of angiogenesis and vascular biology, with potential implications for the development of novel treatments for a range of diseases.
Antibody Name:
THSD1 Antibody (PACO17240)
Antibody SKU:
PACO17240
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse
Immunogen:
Fusion protein of human THSD1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO17240(THSD1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200).
Background:
The protein encoded by this gene contains a type 1 thrombospondin domain, which is found in a number of proteins involved in the complement pathway, as well as in extracellular matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene.
Synonyms:
thrombospondin, type I, domain containing 1
UniProt Protein Function:
THSD1: contains a type 1 thrombospondin domain, which is found in a number of proteins involved in the complement pathway, as well as in extracellular matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jan 2009]Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 13q14.3Cellular Component: cytoplasm
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene contains a type 1 thrombospondin domain, which is found in a number of proteins involved in the complement pathway, as well as in extracellular matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jan 2009]
