The TMX1 Antibody (CAB17219) is a high-quality antibody developed for reliable detection and analysis of target proteins. This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides. RRID AB_2772649 Gene ID 81542 Swiss Prot Synonym TMX; TXNDC; PDIA11; TXNDC1; TMX1
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
TMX1 Antibody
SKU:
CAB17219
Size:
100μL, 20μL
Reactivity:
Human
Clone Number:
-
Conjugate:
-
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:500 - 1:2000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
TMX, TXNDC, PDIA11, TXNDC1, TMX1
Positive Sample:
293T, LO2, HeLa, Jurkat
Cellular Localization:
Endoplasmic Reticulum Membrane, Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:
32kDa
Observed MW:
35kDa
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides. RRID AB_2772649 Gene ID 81542 Swiss Prot Synonym TMX; TXNDC; PDIA11; TXNDC1; TMX1
Purification Method:
Affinity purification
Gene ID:
81542
RRID:
AB_2772649
Buffer Information:
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TMX1 Rabbit pAb (CAB17219) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
