The TWEAKR/Fn14/CD266 Antibody (CAB13093) is a high-quality antibody developed for reliable detection and analysis of target proteins. This cell surface receptor is known to play a role in various biological processes, including the regulation of immune responses and apoptosis. Raised in rabbits, this polyclonal antibody is highly specific and reactive with human samples, making it suitable for use in a variety of research applications such as Western blot and immunohistochemistry. By targeting the TNFRSF12A protein, researchers can detect and analyze its expression in different cell types, providing valuable insights into its function in health and disease.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
TWEAKR/Fn14/CD266 Antibody
SKU:
CAB13093
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
FN14, CD266, TWEAKR, TWEAKR/Fn14/CD266
Positive Sample:
HT-1080
Cellular Localization:
Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:
14kDa
Observed MW:
14kDa
Involved in positive regulation of extrinsic apoptotic signaling pathway and regulation of wound healing. Predicted to be located in cell surface and ruffle. Predicted to be active in plasma membrane.
Purification Method
Affinity purification
Gene ID
51330
RRID
AB_2759942
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HT-1080 cells, using TWEAKR/Fn14/CD266 Rabbit pAb (CAB13093) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
