The TOMM40 Antibody (CAB3213) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity and reactivity with human samples, making it ideal for Western blot applications. By targeting the TOMM40 protein, researchers can effectively analyze and detect its expression in various cell types.TOMM40, also known as the Translocase of Outer Mitochondrial Membrane 40, is crucial for mitochondrial protein import and function, making it a vital component of cellular energy production and metabolism. Recent studies have identified TOMM40 as a potential biomarker for Alzheimer's disease, linking its dysfunction to the progression of this neurodegenerative disorder.
This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
TOMM40 Antibody
SKU:
CAB3213
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
The protein encoded by this gene is localized in the outer membrane of the mitochondria. It is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for import of protein precursors into mitochondria. Alternatively spliced transcript variants have been found for this gene.
Purification Method
Affinity purification
Gene ID
10452
RRID
AB_2764992
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using TOMM40 Rabbit pAb (CAB3213) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
Confocal immunofluorescence analysis of U2OS cells using TOMM40 Rabbit pAb (CAB3213) at dilution of 1:200. Blue: DAPI for nuclear staining.
