The TPD52L2 Polyclonal Antibody (PACO52018) is a valuable tool for researchers studying TPD52L2, a protein associated with cancer progression and metastasis. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the TPD52L2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in oncology and cancer research.
TPD52L2, also known as tumor protein D53, is known to play a crucial role in promoting tumor growth and metastasis in various cancers. Its overexpression has been linked to poor prognosis in patients, highlighting the importance of understanding its function and regulation. Research into TPD52L2 may provide valuable insights into the mechanisms underlying cancer progression and aid in the development of novel therapeutic strategies targeting this protein.
Immunohistochemistry of paraffin-embedded human pancreatic cancer using PACO52018 at dilution of 1:100.
Immunofluorescent analysis of HepG2 cells using PACO52018 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human spleen tissue using PACO52018 at dilution of 1:100.
Background:
cytoplasm, perinuclear region of cytoplasm, poly(A) RNA binding, protein heterodimerization activity, protein homodimerization activity, regulation of cell proliferation
Synonyms:
Tumor protein D54 (hD54) (Tumor protein D52-like 2), TPD52L2
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the tumor protein D52-like family. These proteins are characterized by an N-terminal coiled-coil motif that is used to form homo- and heteromeric complexes with other tumor protein D52-like proteins. Expression of this gene may be a marker for breast cancer and acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 12. [provided by RefSeq, Aug 2011]
