The TSC22D3 Antibody (CAB6779) is a high-quality antibody developed for reliable detection and analysis of target proteins. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the TSC22D3 protein, this antibody allows for the detection and analysis of TSC22D3 levels in various cell types, making it ideal for studies in immunology, inflammation, and cancer research.TSC22D3, also known as glucocorticoid-induced leucine zipper protein, is a key regulator of immune response and has been implicated in the pathogenesis of inflammatory diseases and cancer.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
TSC22D3 Antibody
SKU:
CAB6779
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:
MDLV KNHL MYAV REEV EILK EQIR ELVE KNSQ LERE NTLL KTLA SPEQ LEKF QSCL SPEE PAPE SPQV PEAP GGSA V
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:500 - 1:1000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
DIP, GILZ, DSIPI, TSC-22R, TSC22D3
Positive Sample:
293T, Mouse spleen
Cellular Localization:
Cytoplasm, Nucleus.
Calculated MW:
15kDa
Observed MW:
15kDa
This gene encodes the anti-inflammatory protein glucocorticoid (GC)-induced leucine zipper. Expression of this gene stimulated by glucocorticoids and interleukin 10 and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid. This protein has also been shown to inhibit pro-inflammatory molecules including nuclear factor κB. Alternate splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
1831
RRID
AB_2767362
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from 293T cells, using TSC22D3 Rabbit pAb (CAB6779) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
