The UCHL3 Antibody (CAB8156) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.UCHL3, also known as ubiquitin carboxyl-terminal hydrolase isozyme L3, plays a significant role in protein turnover by removing ubiquitin molecules from targeted proteins, thereby controlling their degradation and recycling. Dysregulation of UCHL3 has been implicated in the development of various diseases, including neurodegenerative disorders and cancer.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
UCHL3 Antibody
SKU:
CAB8156
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
UCH-L3, UCHL3
Positive Sample:
SH-SY5Y, HT-29, Mouse skeletal muscle, Mouse testis, Rat testis
Cellular Localization:
Cytoplasm.
Calculated MW:
26kDa
Observed MW:
26kDa
The protein encoded by this gene is a member of the deubiquitinating enzyme family. Members of this family are proteases that catalyze the removal of ubiquitin from polypeptides and are divided into five classes, depending on the mechanism of catalysis. This protein may hydrolyze the ubiquitinyl-N-epsilon amide bond of ubiquitinated proteins to regenerate ubiquitin for another catalytic cycle. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Purification Method
Affinity purification
Gene ID
7347
RRID
AB_2772794
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
