The UPP1 Antibody (CAB13051) is a high-quality antibody developed for reliable detection and analysis of target proteins. Raised in rabbits, this antibody is highly specific and reacts strongly with human samples, making it ideal for Western blot applications.UPP1 plays a crucial role in the salvage pathway for nucleotide biosynthesis, making it a promising target for studies in cancer research, metabolic disorders, and nucleoside-based therapies.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
UPP1 Antibody
SKU:
CAB13051
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
UP, UPP, UPASE, UDRPASE, UPP1
Positive Sample:
HT-29, A-431, A-549, 293T, HeLa
Cellular Localization:
Cytosol, Nucleoplasm.
Calculated MW:
34kDa
Observed MW:
36kDa
This gene encodes a uridine phosphorylase, an enzyme that catalyzes the reversible phosphorylation of uridine (or 2'- deoxyuridine) to uracil and ribose-1-phosphate (or deoxyribose-1-phosphate). The encoded enzyme functions in the degradation and salvage of pyrimidine ribonucleosides.
Purification Method
Affinity purification
Gene ID
7378
RRID
AB_2759899
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using UPP1 Rabbit pAb (CAB13051) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
