The UQCRB Antibody (CAB1273) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the UQCRB protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in the fields of biochemistry and mitochondrial biology.UQCRB, also known as Ubiquinol-Cytochrome c Reductase Binding Protein, plays a crucial role in electron transport within the mitochondria, contributing to ATP production and cellular energy metabolism.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
UQCRB Antibody
SKU:
CAB1273
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
LO2, MCF7, HL-60, HeLa, Mouse liver, Mouse small intestine, Mouse brain, Mouse kidney, Rat liver
Cellular Localization:
Mitochondrion Inner Membrane.
Calculated MW:
14kDa
Observed MW:
14kDa
This gene encodes a subunit of the ubiquinol-cytochrome c oxidoreductase complex, which consists of one mitochondrial-encoded and 10 nuclear-encoded subunits. The protein encoded by this gene binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. This protein plays an important role in hypoxia-induced angiogenesis through mitochondrial reactive oxygen species-mediated signaling. Mutations in this gene are associated with mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene. Related pseudogenes have been identified on chromosomes 1, 5 and X.
Purification Method
Affinity purification
Gene ID
7381
RRID
AB_2759572
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using UQCRB Rabbit pAb (CAB1273) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
