The UPK2 Antibody (CAB10813) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.Uroplakin-2 is an essential component of the urothelial barrier, helping to maintain the integrity of the bladder lining and prevent microbial infections. Dysregulation of uroplakin-2 expression has been linked to various urological disorders, making it a crucial target for investigation in both basic science and clinical research.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
UPK2 Antibody
SKU:
CAB10813
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
UP2, UPII, UPK2
Positive Sample:
B-cell
Cellular Localization:
Cell Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:
19kDa
Observed MW:
19kDa
This gene encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is believed to strengthen the urothelium by preventing cell rupture during bladder distention. The encoded protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas.
Purification Method
Affinity purification
Gene ID
7379
RRID
AB_2758241
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from B-cell cells, using UPK2 Rabbit pAb (CAB10813) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 40s.
