The USP24 Monoclonal Antibody (CAB0621) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody, generated in rabbits, is highly specific for USP24 and is validated for use in various applications, including Western blotting. By targeting USP24, this antibody allows for precise detection and analysis of the protein in a wide range of cell types.USP24 is known for its involvement in the ubiquitin-proteasome system, playing a vital role in the regulation of protein degradation and turnover. Dysregulation of USP24 has been linked to various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
USP24 Monoclonal Antibody
SKU:
CAB0621
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC2526
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
USP24, ubiquitin specific peptidase 24
Positive Sample:
HeLa, Jurkat, SH-SY5Y, Mouse liver, Mouse thymus, Rat liver
Cellular Localization:
Cytosol, Nucleoplasm, Nucleus.
Calculated MW:
294kDa
Observed MW:
295kDa
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).
Purification Method
Affinity purification
Gene ID
23358
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using USP24 Rabbit mAb (CAB0621) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
