The VDAC1 Polyclonal Antibody (CAB13638) is a valuable tool for researchers studying the voltage-dependent anion channel 1 (VDAC1), a crucial protein involved in mitochondrial function and cell metabolism. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications.VDAC1 is known to play a key role in regulating mitochondrial energy metabolism, apoptosis, and cell survival. Dysregulation of VDAC1 has been implicated in various diseases, including cancer, neurodegenerative disorders, and metabolic conditions.
By targeting VDAC1 with this polyclonal antibody, researchers can better understand its function and potential therapeutic implications.This VDAC1 Polyclonal Antibody is essential for studies in mitochondrial biology, cancer research, and neurodegenerative diseases. Its specificity and reliability make it an ideal tool for detecting and analyzing VDAC1 expression in different cell types, providing valuable insights into the role of this protein in health and disease.
Product Name:
VDAC1/Porin Rabbit Polyclonal Antibody
SKU:
CAB13638
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human VDAC1 / Porin (NP_003365.1).
This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.
Purification Method:
Affinity purification
Gene ID:
7416
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using VDAC1 / Porin antibody (CAB13638) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
