The VSIG8 Polyclonal Antibody (PACO60096) is an essential tool for researchers studying VSIG8, a cell surface protein involved in immune regulation and immune response modulation. This antibody, produced in rabbits, is highly specific to human VSIG8 and is suitable for use in Western blot applications. By binding to the VSIG8 protein, this antibody allows for the detection and analysis of VSIG8 in various cell types, making it an ideal choice for studies in immunology and cancer research.VSIG8, also known as V-set and immunoglobulin domain containing 8, has been identified as a promising target for research into immune-related diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
Its role in immune regulation and immune response modulation highlights its potential as a therapeutic target for the development of novel treatment strategies. By gaining insights into the function of VSIG8, researchers can further understand its impact on immune homeostasis and pave the way for the development of innovative immunotherapies.
IHC image of PACO60096 diluted at 1:400 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunofluorescence staining of Hela cells with PACO60096 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
RNA binding
Synonyms:
V-set and immunoglobulin domain-containing protein 8, VSIG8, C1orf204
UniProt Protein Function:
VSIG8: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 1q23.2Cellular Component: integral to membrane; intracellular
