The WIPI1 Monoclonal Antibody (CAB9600) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity for WIPI1 in a variety of experimental settings.WIPI1 is known to play a crucial role in the formation of pre-autophagosomal structures, leading to the initiation of autophagy, a cellular process crucial for maintaining cellular homeostasis and responding to stress conditions. Dysregulation of WIPI1 has been implicated in various diseases, including neurodegenerative disorders and cancer.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
WIPI1 Monoclonal Antibody
SKU:
CAB9600
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC1652
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
This gene encodes a WD40 repeat protein. Members of the WD40 repeat family are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
55062
RRID
AB_2863733
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using WIPI1 Rabbit mAb (CAB9600) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90 s.
