The XKR7 Polyclonal Antibody (PAC020937) is a valuable tool for researchers studying the XKR7 protein, a member of the XK family of putative transporters. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the XKR7 protein, this antibody enables researchers to detect and analyze the expression of XKR7 in various cell types, making it ideal for investigations in the fields of cell biology and genetics.XKR7 is known to play a role in cellular transport processes, potentially influencing cell membrane dynamics and lipid metabolism.
Understanding the function of XKR7 is important for unraveling its role in cellular physiology and disease development. Research on XKR7 may provide insights into its potential implications in diseases such as cancer, neurodegenerative disorders, and metabolic syndromes. By utilizing the XKR7 Polyclonal Antibody, researchers can further explore the intricate functions of the XKR7 protein and its impact on various cellular processes.
Antibody Name:
XKR7 Antibody (PACO20937)
Antibody SKU:
PACO20937
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic peptide of human XKR7
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO20937(XKR7 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using PACO20937(XKR7 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
XKR7 (XK-related protein 7) is a 579 amino acid, multi-pass membrane protein that likely is a component of the XK/Kell complex of the Kell blood group system. The gene encoding XKR7 maps to human chromosome 20, which comprises approximately 2% of the human genome. Chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome.
Synonyms:
XK, Kell blood group complex subunit-related family, member 7
UniProt Protein Function:
XKR7: Belongs to the XK family.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 20q11.21Cellular Component: integral to membrane
