The XPO6 Polyclonal Antibody (CAB24463) is a high-quality antibody developed for reliable detection and analysis of target proteins. This rabbit polyclonal antibody is highly specific to human samples and has been validated for use in Western blot applications. It binds to the XPO6 protein, enabling researchers to detect and analyze its expression in various cell types.XPO6 is involved in the transportation of proteins and RNA molecules between the nucleus and cytoplasm, making it essential for cellular functions such as gene expression and signal transduction. Dysregulation of XPO6 has been linked to various diseases, including cancer and neurodegenerative disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
XPO6 Polyclonal Antibody
SKU:
CAB24463
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
XPO6, EXP6, RANBP20, exportin-6
Positive Sample:
293F, HeLa, OVCAR-3, Mouse testis, Mouse thymus
Cellular Localization:
Cytoplasm, Nucleus.
Calculated MW:
127kDa/128kDa
Observed MW:
128kDa
The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Purification Method
Affinity purification
Gene ID
23214
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using XPO6 Rabbit pAb (CAB24463) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
