The XPO7 Antibody (CAB16108) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications. By binding specifically to the XPO7 protein, researchers can effectively detect and analyze its expression in various cell types, making it an invaluable resource for studies in molecular biology and cell biology.XPO7, also known as Exportin-7, is a critical regulator of nucleocytoplasmic transport, facilitating the movement of proteins and RNAs between the nucleus and cytoplasm.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
XPO7 Antibody
SKU:
CAB16108
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
EXP7, RANBP16, XPO7
Positive Sample:
LO2, HT-29, Mouse testis, Mouse spleen, Mouse liver, Rat testis
Cellular Localization:
Cytoplasm, Nucleus, Nuclear Pore Complex.
Calculated MW:
124kDa
Observed MW:
124kDa
The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-16 is a member of the importin-beta superfamily of nuclear transport receptors.
Purification Method
Affinity purification
Gene ID
23039
RRID
AB_2763551
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using XPO7 Rabbit pAb (CAB16108) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
