The ZBTB2 Polyclonal Antibody (PAC020943) is a valuable tool for researchers studying the ZBTB2 protein, a transcriptional regulator involved in various cellular processes, including cell growth and differentiation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By binding to the ZBTB2 protein, this antibody enables researchers to detect and analyze its expression in different cell types, making it ideal for studies in molecular biology and cancer research.ZBTB2, also known as Zinc finger and BTB domain-containing protein 2, plays a crucial role in gene regulation and cellular development.
Its involvement in processes such as cell cycle control and apoptosis makes it a promising target for investigating diseases like cancer and developmental disorders. Understanding the functions of ZBTB2 is essential for gaining insights into its potential therapeutic implications in various pathological conditions.Overall, the ZBTB2 Polyclonal Antibody offers researchers a reliable tool for exploring the role of ZBTB2 in cellular biology and disease mechanisms, paving the way for innovative research and potential clinical applications.
Antibody Name:
ZBTB2 Antibody (PACO20943)
Antibody SKU:
PACO20943
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:30-1:150
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human ZBTB2
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20943(ZBTB2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO20943(ZBTB2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
ZBTB2 is a 514 amino acid, nuclear protein that contains one BTB (POZ) domain and 4 C2H2-type zinc fingers. ZBTB25, also known as ZNF46 or KUP, is a 435 amino acid, nuclear protein that is expressed mainly in hematopoietic cells and testis and contains one BTB (POZ) domain and 2 C2H2-type zinc fingers.
Synonyms:
zinc finger and BTB domain containing 2
UniProt Protein Function:
ZBTB2: May be involved in transcriptional regulation.Protein type: C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 6q25.1Molecular Function: protein binding
