The ZC4H2 Polyclonal Antibody (PACO48122) is a valuable tool for researchers studying ZC4H2, a protein involved in RNA metabolism and neural development. This antibody, produced in rabbits, specifically recognizes ZC4H2 in human samples and is validated for use in Western blot applications. By targeting the ZC4H2 protein, researchers can investigate its role in various cellular processes and pathways related to neurological disorders and RNA processing.ZC4H2, also known as zinc finger C4H2 domain-containing protein, has been implicated in neurological disorders such as X-linked intellectual disability.
Studies have shown that mutations in the ZC4H2 gene can disrupt normal neurological development, making it a promising target for further research in neurobiology and genetic disorders. By using the ZC4H2 Polyclonal Antibody, researchers can gain insights into the function and dysfunction of ZC4H2 in disease contexts, ultimately paving the way for potential therapeutic interventions.
ZC4H2: a member of the zinc finger domain-containing protein family. This family member has a C-terminal zinc finger domain that is characterized by four cysteine residues and two histidine residues, and it also includes a coiled-coil region. This protein has been detected as an autoantigen in hepatocellular carcinoma patients. This gene has been identified as a potential candidate for X-linked mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]Chromosomal Location of Human Ortholog: Xq11.2Cellular Component: cytoplasm; nucleus; postsynaptic membraneMolecular Function: protein bindingBiological Process: nervous system development; neuromuscular junction development; spinal cord motor neuron differentiation
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the zinc finger domain-containing protein family. This family member has a C-terminal zinc finger domain that is characterized by four cysteine residues and two histidine residues, and it also includes a coiled-coil region. This protein has been detected as an autoantigen in hepatocellular carcinoma patients. This gene has been identified as a potential candidate for X-linked mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
