The ZNF146 Polyclonal Antibody (PAC020961) is a valuable tool for research involving ZNF146, a zinc finger protein known to play a role in gene regulation and cellular processes. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it suitable for use in various research applications such as Western blotting. By binding to the ZNF146 protein, this antibody allows for the identification and analysis of ZNF146 in different cell types, making it a valuable asset for studies in molecular biology and genetic regulation.
ZNF146 is a transcription factor that has been implicated in the regulation of gene expression and cell growth, making it a target of interest in cancer research and developmental biology. Understanding the function and activity of ZNF146 can provide valuable insights into cellular processes and may lead to the development of novel therapeutic strategies for diseases related to gene dysregulation. This ZNF146 antibody is a reliable tool for researchers seeking to uncover the role of ZNF146 in various biological pathways and disease conditions.
Antibody Name:
ZNF146 Antibody (PACO20961)
Antibody SKU:
PACO20961
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:1000-1:2000, WB:1:200-1:1000
Species Reactivity:
Human, Mouse
Immunogen:
Synthetic peptide of human ZNF146
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane 1-2: 231 and K562 cell, Primary antibody: PACO20961(ZNF146 Antibody) at dilution 1/200 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds.
Background:
ZNF146 (zinc finger protein 146), also known as OZF (only zinc finger protein), is a 292 amino acid, nuclear protein that binds DNA and belongs to the Kr¼ppel C2H2-type zinc-finger protein family. ZNF146 interacts with UBC9 (ubiquitin carrier protein 9) and RAP1 (repressor/activator protein 1 homolog), and is highly expressed in multiple pancreatic and colorectal cancers. Lower levels of expression have been observed in kidney, lung, placenta and brain.
Synonyms:
zinc finger protein 146
UniProt Protein Function:
ZNF146: Belongs to the krueppel C2H2-type zinc-finger protein family.Protein type: DNA-binding; C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 19q13.1Cellular Component: cytoplasm; nucleolus; nucleusMolecular Function: heparin binding; transcription factor activity; zinc ion bindingBiological Process: regulation of transcription, DNA-dependent
