The ZNHIT6 Polyclonal Antibody (PACO22704) is a valuable tool for researchers studying ZNHIT6, a protein involved in chromatin remodeling and gene regulation. This antibody, generated in rabbits, shows high specificity for ZNHIT6 in human samples and has been validated for use in Western blot applications. By binding to ZNHIT6, researchers can easily detect and analyze the protein in various cell types, making it ideal for studies in molecular biology and epigenetics.ZNHIT6 is known to play a critical role in regulating gene expression by modifying chromatin structure, thereby influencing important cellular processes such as gene transcription and DNA repair.
Research on ZNHIT6 is vital for understanding its impact on cell function and how dysregulation of this protein may contribute to diseases such as cancer, aging, and neurological disorders. By investigating the function of ZNHIT6, researchers can uncover potential therapeutic targets for addressing these conditions.In conclusion, the ZNHIT6 Polyclonal Antibody (PACO22704) is a reliable tool for studying the role of ZNHIT6 in various biological processes and disease pathways. Its specificity and sensitivity make it a valuable asset for researchers aiming to uncover new insights into chromatin remodeling and gene regulation mechanisms.
Antibody Name:
ZNHIT6 Antibody (PACO22704)
Antibody SKU:
PACO22704
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from internal of human CA181.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from Jurkat cells and HeLa cells, using CA181 antibody.
Background:
Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.
Synonyms:
HIT-type zinc finger-containing protein C1orf181; HIT-type zinc finger-containing protein C1orf181; C1orf181;
UniProt Protein Function:
ZNHIT6: Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis. Belongs to the BCD1 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 1p22.3Molecular Function: ATPase binding; enzyme binding; identical protein binding; protein bindingBiological Process: box C/D snoRNP assembly; protein oligomerization; snoRNA localization
