Description
ABCA4 Antibody (CAB10556)
The ABCA4 Antibody (CAB10556) is a high-quality antibody developed for reliable detection and analysis of target proteins. Developed through immunization of rabbits, this antibody exhibits high reactivity with human samples and has been validated for Western blot applications. By specifically binding to the ABCA4 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an excellent choice for research in ophthalmology and lipid metabolism.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
| Product Name: | ABCA4 Antibody |
| SKU: | CAB10556 |
| Size: | 20μL, 100μL |
| Reactivity: | Human, Mouse, Rat |
| Conjugate: | Unconjugated |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. | ||||
| Sequence: | QELL MNAP ESQH LGRI WTEL HILS QFMD TLRT HPER IAGR GIRI RDIL KDEE TLTL FLIK NIGL SDSV VYLL INSQ VRPE QFAH GVPD LALK DIAC SEAL LERF IIFS QRRG AKTV RYAL CSLS QGTL QWIE DTLY ANVD FFKL FRVL PTLL DSRS QGIN LRSW GGIL SDMS PRIQ EFIH RPSM QDLL WVT | ||||
| Tested Applications: | WB ELISA | ||||
| Recommended Dilution: |
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| Synonyms: | FFM, RMP, ABCR, RP19, STGD, ABC10, ARMD2, CORD3, STGD1, ABCA4 |
| Positive Sample: | Mouse eye |
| Cellular Localization: | Membrane, Multi-Pass Membrane Protein. |
| Calculated MW: | 256kDa |
| Observed MW: | 256kDa |
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, and the gene product mediates transport of an essental molecule, all-trans-retinal aldehyde (atRAL), across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2.
| Purification Method | Affinity purification |
| Gene ID | 24 |
| RRID | AB_2758098 |
| Buffer Information | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3. |
