The ABHD12 Antibody (CAB17678) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, specifically raised in rabbits, is highly sensitive and specific for detecting ABHD12 protein in human samples, making it an ideal choice for Western blot applications. By targeting the ABHD12 protein, researchers can explore its role in various cellular processes and disease mechanisms, particularly in the fields of lipid metabolism, neurobiology, and cancer research.ABHD12, a member of the α/β-hydrolase domain-containing protein family, is known to play a crucial role in lipid metabolism and signaling cascades, making it a potential target for therapeutic interventions in metabolic disorders and cancer.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Rat samples.
Product Name:
ABHD12 Antibody
SKU:
CAB17678
Size:
20μL, 100μL
Reactivity:
Human, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Purification Method
Affinity purification
Gene ID
26090
RRID
AB_2768187
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ABHD12 Rabbit pAb (CAB17678) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
