The ADRA2C Antibody (CAB16956) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications.By specifically binding to the Adra2c protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for studies in neuroscience, pharmacology, and endocrinology. The Adra2c receptor is known for its role in modulating stress responses, blood pressure regulation, and behavioral functions, making it a promising target for research into conditions such as anxiety disorders, hypertension, and depression.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
ADRA2C Antibody
SKU:
CAB16956
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
ADRA2L2, ADRARL2, ADRA2RL2, ALPHA2CAR, ADRA2C
Positive Sample:
293T, Mouse brain
Cellular Localization:
Cytoplasm, Endosome, Plasma Membrane.
Calculated MW:
50kDa
Observed MW:
50kDa
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.
Purification Method
Affinity purification
Gene ID
152
RRID
AB_2768268
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ADRA2C Rabbit pAb (CAB16956) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
